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How Snakes Resist Their Own Venom: Protein Combinations Could Inspire Better Antivenoms
Natural resistance to venom in snakes may offer a route toward more effective antivenoms. Researchers studying the western diamondback rattlesnake (Crotalus atrox) examined metalloproteinase-inhibiting proteins circulating in its blood. Individually, some of these proteins provided only modest protection. In specific combinations, however, their venom-neutralizing effect increased sharply. Laboratory work reported strong activity against multiple venoms,…